What is Alzheimer’s Disease?
Alzheimer’s disease (AD) is the most common cause of cognitive deterioration in the elderly affecting approximately 27 million people worldwide. By 2050, the number of people with this progressive and debilitating neurological disease is expected to quadruple.
Symptoms of Alzheimer’s disease include:
- Memory loss
- Spatial disorientation
- Difficulty speaking & expressing thoughts
- Chronic fatigue
- Social withdrawal
How is Alzheimer’s Disease Linked to Mitochondrial Dysfunction?
While the formation of beta-amyloid plaques in brain cells is currently the prevailing hypothesis for how Alzheimer’s disease develops, oxidative damage with a subsequent decline in the brain cell’s ability to produce adequate energy (ATP), is currently being investigated as a preliminary step which leads to the formation of beta-amyloid plaques.